Cardinals vs. Brewers odds, line, prediction: 2022 MLB picks, April 14 best bets from proven computer model

ByFreda D. Cuevas

Apr 16, 2022 , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,


Milwaukee will be looking to extend its two-game winning streak when it hosts St. Louis on Thursday night. This will be the first meeting of a four-game series between the National League Central rivals. St. Louis has won six of the last seven head-to-head meetings, including four of the last five in Milwaukee. Veteran right-hander Adam Wainwright is going to start on the mound for the Cardinals, while two-time All-Star Brandon Woodruff is starting for the Brewers.

First pitch is set for 5:14 p.m. ET from American Family Field in Milwaukee. Milwaukee is listed as the -140 favorite (risk $140 to win $100) in the latest Cardinals vs. Brewers odds from Caesars Sportsbook, with the over-under set at eight runs. Before making any Brewers vs. Cardinals picks, you need to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every game 10,000 times, enters Week 2 of the 2022 season on a 216-181 roll on top-rated MLB money-line picks that dates back to last season, returning over $900 for $100 players. Anyone following it has seen huge returns.

Now, the model has locked in on Cardinals vs. Brewers, and just locked in its picks and MLB predictions. You can visit SportsLine now to see the model’s picks. Here are the MLB odds and trends for Brewers vs. Cardinals:

  • Cardinals vs. Brewers money line: Milwaukee -140, St. Louis +120
  • Cardinals vs. Brewers run-line: Milwaukee -1.5 (+140)
  • Cardinals vs. Brewers over-under: 8 runs
  • STL: Cardinals are 2-2 ATS this season
  • MIL: Brewers are 1-5 ATS this season

Featured Game | Milwaukee Brewers vs. St. Louis Cardinals

Why you should back the Cardinals

St. Louis is off to a hot start in 2022, winning three of its first four games. The Cardinals also got an unexpected off day on Wednesday following a weather-induced postponement. They have their top starting pitcher on the mound in this game, as Wainwright was the Opening Day starter. 

Wainwright was fantastic in that start, throwing six shutout innings in a win over Pittsburgh. He has been excellent against Milwaukee during his career, going 20-12 with a 2.60 ERA in 49 career appearances. The Cardinals have been getting off to a strong start in all of their games, scoring a first-inning run in each of their four contests. 

Why you should back the Brewers

Milwaukee got off to a slow start this season, but it has bounced back with a two-game winning streak. Designated hitter Andrew McCutchen has been a welcomed addition to the lineup, racking up six hits in his first 24 at-bats with the team. Shortstop Willy Adames also has six hits, while Christian Yelich has five base knocks and five walks.

The Brewers can expect a much better start from Woodruff than he had on Opening Day. He finished last season with a 2.56 ERA, which was fourth best in the major leagues. Woodruff has had success against St. Louis during his career, going 3-3 with a 3.30 ERA in 10 career games. 

How to make Brewers vs. Cardinals picks

SportsLine’s model is leaning over on the run total, as the simulation suggests the teams will combine for 8.6 runs. It also says one side of the money line has all the value. You can only get the model’s pick at SportsLine

So who wins Cardinals vs. Brewers? And which side of the money line has all the value? Visit SportsLine now to see which side to jump on, all from the advanced model that has crushed its top-rated MLB picks, and find out.


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